I print out invoices and file those. I look at lots of other reports online (sales, P&L, etc.), but don’t print any of those out unless it’s for my accountant to look at before she sees the final QB file for end-of-year tax handling. I write checks by hand (not many of those) and I handle payroll using an online service.

I visit with my accountant once a year for taxes. The rest of the time, we e-mail or chat by phone when questions come up (most recent question: how to create a medical reimbursement plan?).

I highly recommend off-site backup if you have a broadband Internet connection. Companies like Mozy and Box.net (a couple of our sponsors) as well as IronMountain provide a way to remotely backup your data to their servers. That way, you’re protected from computer crashes, fires, theft, flood, whatever. The prices are quite reasonable compared to the cost of trying to recover your business in case something bad happens.